Antitumor and anti-angiogenic activity of Ganoderma lucidum polysaccharides peptide. Ganoderma lucidum inhibits proliferation and induces apoptosis in human prostate cancer cells PC Ganoderma lucidum extract induce cell cycle arrest an apoptosis in MCF-7 human breast cancer cell. Biologic activity spores and dried powder from Ganoderma lucidum for the inhibition of a highly invasive human breast and prostate cancer cells. J Altern Complement Med. Anti-tumor and inmunoregulatory activities of Ganoderma lucidum and its possible mechanisms.
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View All Reishi is a type of mushroom used to promote health and longevity in traditional Chinese medicine and Ayurvedic medicine. Also known as the lingzhi mushroom, reishi had a red, kidney-shaped cap and finger-like spores on its underside rather than gills. The species of reishi most commonly used for medicine is Ganoderma lucidum.
Many of the purported benefits of reishi are attributed to a group of compounds called ganoderic acids, which have a similar structure to steroid hormones. Reishi is also rich in beta-glucans which can help improve cholesterol and glucose levels. However, it is can be used to make tea or medicinal tonics. The term "lingzhi" was derived from the Chinese words ling meaning spirit and zhi meaning plant. The Japanese "reishi" is more commonly used today, the term of which is loosely adapted from "lingzhi.
Others have ascribed it with "cure-all" properties that are far-reaching in their scope. Reishi is purported to help control blood sugar levels, liver problems, immune system issues, and as an antibiotic. Of the studies currently available, most are limited to test tubes or small-scale animal or human trials. While some of the results are promising, none are robust enough to recommend reishi as a treatment for any medical condition. While promising, the same level of control has not been seen outside of the test tube.
An earlier study in by the same team reported that a G. Bacterial Infections There is even less evidence supporting the antibacterial effects of reishi. Although there have several studies demonstrating how G. Of the available studies, an early investigation in from Japan reported that a 2-milligram injection of G. Other studies have found no effect, whether the extract was delivered orally or by injection. Further research is needed to substantiate these findings.
In the lab, reishi has been shown to kill tumor cells and boost the activity of immune cells such as natural killer cells NK , T-cells , B-cells, tumor necrosis factor TNF , and phagocytes which ingest other cells. The results of the studies were largely mixed and often contradictory.
One of the reviewed studies reported an increase in NK cells; another showed no response. A slightly larger number of people on chemotherapy reported a better quality of life when taking G. Few side effects were reported in any of the studies. The investigators stated the quality of the studies ranged from low to very low.
Possible Side Effects Reishi is usually well-tolerated with few significant side effects. Reishi also contains a substance that may act like a blood thinner, potentially triggering bloody stools, nosebleeds, and easy bruising. It should not be used if you are taking anticoagulants like warfarin or are scheduled to have surgery as it may increase the risk of bleeding. Reishi may also cause your blood pressure to drop and should be avoided if you are taking antihypertensive medications.
Doing so may lead to hypotension low blood pressure , triggering dizziness, fatigue, nausea, and blurry vision. Due to the lack of safety research, reishi should be avoided in children, pregnant women, and breastfeeding mothers. Dosage and Preparation There are no guidelines directing the appropriate use of reishi. Most reishi supplements are available in capsule form and are considered safe in daily doses of 1. Reishi products are readily found online and in health food stores and specialty supplements retailers.
Always opt for products that are certified organic under the regulations of the U. This can reduce your risk of exposure to pesticides and other toxins, particularly in imported herbal remedies. Because herbal medicines do not have to undergo the rigorous testing and research that pharmaceutical drugs do, the quality can vary considerably.
Some labeled "reishi" may not contain any G. Unfortunately, few herbal manufacturers voluntarily submit the products for inspection by certifying bodies like the U. Pharmacopeia USP. Other Questions Are fresh reishi mushrooms available? Fresh reishi mushrooms are harder to find in the United States than dried ones.
A number of domestic growers have begun to cultivate them, mainly in the Pacific Northwest, but reliable suppliers are few and far between. There are kits you can buy online that enable to grow your own reishi mushrooms. They are relatively easy to use and not all that costly. Be aware that the mushrooms grow very slowly and may take six months or more before you are ready to harvest any. If growing reishi is too much of a hassle, the dried mushrooms are believed to be just as beneficial as fresh ones.
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